Figure 2. Concentration-dependent effect of MMC on corneal fibroblast viability. Cells were incubated with various concentrations of MMC for 24 h after which cell viability was measured using MTT and LDH assays. The MTT assay demonstrated fewer viable GCD II homozygote cells than normal cells in all concentrations. Upper panel=MTT assay, lower panel=LDH assay. The asterisk indicates a p<0.05; ANOVA. MMC: mitomycin C, control: without MMC, NR: normal, HE: heterozygote, HO: homozygote.