Figure 1. Time course for the effect of 0.02% MMC on corneal fibroblast viability. Corneal fibroblasts were incubated with 0.02% MMC for various times after which cell viability was measured using MTT and LDH assays. The MTT and LDH assays demonstrated some minor differences, there were fewer viable GCD II homozygote cells than normal cells. Upper panel=MTT assay, lower panel=LDH assay. The asterisk indicates a p<0.05; ANOVA. MMC: mitomycin C, control: without MMC, NR: normal, HE: heterozygote, HO: homozygote.