Table 4 of Clement, Mol Vis 2008; 14:1209-1221.

Table 4. Subset of genes whose expression was altered more than 4 fold in the rabbit HSV-1 latent trigeminal ganglia

Probe name p-value Mean log2 difference Fold change Hit definition Biologic Process E-value
UF_Oc_c_40190 0.001 3.83 14.22 Immunoglobulin Joining Chain Humoral immune response 0
UF_Oc_c_40194 0.004 3.11 8.63 Human Lysozyme Cell wall catabolism; carbohydrate metabolism; cytolysis 0
UF_Oc_n_41508 0.032 2.6 6.06 Cathelicidin Antimicrobial Peptide “Response to pest, pathogen or parasite; defense response to bacteria” 0
UF_Oc_c_40416 0.033 2.08 4.23 Cysteine-rich Secretory Protein 3 Fertilization; innate immune response; cell-cell adhesion; spermatogenesis; defense response 0
UF_Oc_n_41565 0.021 2.07 4.2 Interleukin 1 Beta Apoptosis; cell proliferation; negative regulation of cell proliferation; signal transduction; inflammatory response; regulation of cell cycle; antimicrobial humoral response 0

The genes whose expression was altered by more than 4 fold were all upregulated and had an assigned Gene Ontology term related to host defense and immune response. These genes, interleukin 1 beta (IL1β), cysteine-rich secretory protein 3 (CRISP3), cathelicidin antimicrobial peptide (CAP18), human lysozyme (LYZ), and immunoglobulin joining chain (IGJ), are involved in innate and immune defense response.

Clement, Mol Vis 2008; 14:1209-1221. http://www.molvis.org/molvis/v14/a142

©2008 Molecular Vision http://www.molvis.org/molvis/

ISSN 1090-0535