Figure 1. Gene expression significantly altered in the rabbit HSV-1 latent trigeminal ganglia compared to naïve (uninfected) trigeminal ganglia. Pie chart of gene expression significantly altered in the HSV-1 latent rabbit trigeminal ganglia compared to naïve trigeminal ganglia. Host defense and immune response genes showed the highest percentage of altered genes that were upregulated. The catabolic categories of protein degradation and carbohydrate metabolism showed the highest percentage of altered genes that were downregulated.