Table 2 of Kane, Mol Vis 2008; 14:1138-1148.


Table 2. Differential gene expression in human retinal pericytes exposed to hypoxia.

Number Accession number Description SLR
Upregulated genes
1 NM_000076.1 cyclin-dependent kinase inhibitor 1C (p57, Kip2, CDKN1C) 1.7
2 NM_000963.1 prostaglandin-endoperoxide synthase 2 (prostaglandin GH synthase and cyclooxygenase, PTGS2) 1.43
3 NM_013332.1 hypoxia-inducible protein 2 (HIG2) 1.43
4 BC005254.1 Similar to C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 2 (activation-induced), clone MGC:12289 1.4
5 NM_016109 PPAR(gamma) angiopoietin related protein (PGAR) 1.36
6 AF064238.3 smoothelin large isoform L2 (SMTN) 1.26
7 AF022375.1 vascular endothelial growth factor 1.26
8 NM_014883.1 KIAA0914 gene product (KIAA0914) 1.16
9 NM_015675.1 growth arrest and DNA-damage-inducible, beta (GADD45B) 1.13
10 NM_002166.1 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein (ID2) 1.06
11 NM_017606.1 hypothetical protein DKFZp434K1210 (DKFZp434K1210) 1.06
12 BC005127.1 adipose differentiation-related protein, clone MGC:10598 1.03
13 NM_020142.1 NADH:ubiquinone oxidoreductase MLRQ subunit homolog (LOC56901) 1.03
14 NM_003734.2 amine oxidase, copper containing 3 (vascular adhesion protein 1, AOC3) 1
15 NM_006931.1 solute carrier family 2 (facilitated glucose transporter), member 3 (SLC2A3) 0.96
16 S73751.1 acyl CoA:cholesterol acyltransferase 0.93
17 AL048423.1 EST: integrin, beta 5 0.9
18 NM_003897.1 immediate early response 3 (IER3) 0.9
19 NM_005195.1 CCAATenhancer binding protein (CEBP), delta (CEBPD) 0.9
20 AL049176 DNA sequence from clone 141H5 on chromosome Xq22.1–23. Contains parts of a novel Chordin LIKE protein with von Willebrand factor type C domains. 0.9
21 NM_020639.1 ankyrin repeat domain 3 (ANKRD3) 0.9
22 NM_002912.1 REV3 (yeast homolog)-like, catalytic subunit of DNA polymerase zeta (REV3L) 0.83
23 NM_000954.1 prostaglandin D2 synthase (21kD, brain; PTGDS) 0.83
24 BC000125.1 Similar to transforming growth factor, beta 1, clone MGC:3119 0.76
25 AI078167 EST: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.76
26 NM_005384.1 nuclear factor, interleukin 3 regulated (NFIL3) 0.76
27 NM_019058.1 hypothetical protein (FLJ20500), mRNA. RTP801 0.73
28 NM_003670.1 basic helix-loop-helix domain containing, class B, 2 (BHLHB2) 0.66
Downregulated genes
1 NM_000903.1 diaphorase (NADHNADPH, cytochrome b-5 reductase, DIA4) -2.16
2 NM_003234.1 transferrin receptor (p90, CD71, TFRC) -1.53
3 NM_020299.1 aldo-keto reductase family 1, member B10 (AKR1B10) -1.53
4 NM_018092.1 neuropilin (NRP) and tolloid (TLL)-like 2 (NETO2) -1.23
5 M21692.1 class I alcohol dehydrogenase (ADH2) beta-1 subunit -1
6 D45421.1 mRNA for phosphodiesterase I alpha -0.86
7 AK021882.1 cDNA FLJ11820 fis, clone HEMBA1006445, highly similar to putative tumor supressor NOEY2 -0.76