Table 1 of Gandra, Mol Vis 2008; 14:1105-1113.

Table 1. Number of retinitis pigmentosa genes and loci

Mapped and identified genes CA4, CRX, FSCN2, GUCA1B, IMPDH1, NR2E3, NRL, PRPF3, PRPF8, PRPF31, PRPH2, RHO, ROM1, RP1, RP9, SEMA4A, TOPORS, ABCA4, CERKL, CNGA1, CNGB1, CRB1, LRAT, MERTK, NR2E3, PDE6A, PDE6B, PRCD, PROM1, RGR, RLBP1, RPE65, SAG, TULP1, USH2A, RP2, RPGR 37
Mapped loci (not identified) RP33, RP22, RP25, RP28, RP29, RP32, RP6, RP23, RP24, RP34 10
Total
47

Tremendous research in the field of RP allowed the identification of nearly 47 genes. However, mutations in 37 genes are known to cause adRP and 10 adRP genes have been mapped but not identified yet (RetNet).

Gandra, Mol Vis 2008; 14:1105-1113. http://www.molvis.org/molvis/v14/a131

©2008 Molecular Vision http://www.molvis.org/molvis/

ISSN 1090-0535