Figure 3. IgG subclass of anti-EsteD and anti- brain-type creatine kinase antibodies in experimental autoimmune uveoretinitis mice were determined by ELISA. Concentrations of anti-EsteD and anti- brain-type creatine kinase (BB-CK) IgG1 antibodies in all tested serum samples of experimental autoimmune uveoretinitis were much higher than those of anti-EsteD and anti-BB-CK IgG2a antibodies. All control serum samples collected from mice immunized without hIRBP-p were negative for both IgG1 and IgG2a.