Figure 5 of Vij, Mol Vis 2008; 14:1020-1027.


Figure 5. PDGF-induced cell migration involves JAK2-STAT3 pathway. Human corneal fibroblasts were exposed to PDGF in the presence or absence of JAK2-STAT3 inhibitor, AG-490, for 8 h, and cell migration was quantified using the Boyden chamber chemotaxis assay. PDGF-induced corneal fibroblast migration was inhibited significatly by AG-490. The asterisk indicates a p<0.001 versus control and the double asterisk indicates a p<0.01 versus PDGF.