Figure 1. Effect of the nitric oxide
synthase inhibitor L-NAME on cell coverage in lens epithelial explants.
Explants, initially matched for cell coverage, were cultured in the
control medium (CON) or in the control medium supplemented with L-NAME
or with the negative control D-NAME at a final concentration of 5 mM.
Cell coverage was assessed daily by phase contrast microscopy. Each
value represents the mean±SEM of data from 9 to 12 explants. Explants
cultured with L-NAME had significantly lower cell coverage than the
corresponding control and D-NAME-treated explants on days 4 and 5
(p<0.001, Kruskal–Wallis test with Dunn’s correction for multiple
comparisons). NAME stands for Nω-nitro-L-arginine methyl
ester.