Figure 2. Fundus photographs from RFS169. Right midpheripheral fundus (A) and right peripheral fundus (B) photographs from the 41-year-old sister of the proband from family RFS169. The midperiphery of both eyes contained numerous bone-spicule-like pigment deposits and the retinal arterioles were slightly narrowed by comparison to the veins. There was no evidence of a perivascular cuff of retinal pigment epithelium atrophy around the superior and inferior arcades in this family.