Molecular Vision: Gottipati, Mol Vis 2008; 14:898-905. Table 1

Table 1. 17β-E₂ upregulates manganese superoxide dismutase activity.

Time	U/ml		Time	U/mg protein
Time	Control	(+) 17b E2	Time	Control	(+) 17b E2
30 min	54.9±6.1	67.7±6.5	30 min	24.5±5.3	29.4±5.1
90 min	66.4±9.1	104±12.1*	90 min	27.4±3.8	49.6±7.4*

HLE-B3 cells maintained in 0.5% serum were exposed to 1 μM 17β-E₂ for 30 and 90 min (n=8, from two individual cell populations±SEM). The control represents cells that were not treated with 17β-E₂. Note the significant increase in activity (asterisk) detected with the 90 min incubation treated with 17β-E₂. The MnSOD activity (refer to Methods) was expressed as units/ml (left panel) or units/mg protein (right panel). n=8 from two independent cell populations; the asterisk indicates statistical significance as determined by Student’s t-test.