Figure 6. Effects of tBHP (chemical
oxidant) on retinal epithelial cells. ROS overproduction (dashed line)
and P2X7 receptor activation (full line) are induced by tBHP on retinal
cells. Cells were exposed to various concentrations of tBHP for 1 h.
ROS production and P2X7 pore formation were detected using the H2DCF-DA
(dashed line) and YO-PRO-1 (full line) tests. The asterisk denotes a
p<0.05 and the triple asterisk indicates a p<0.001 compared to