Table 3 of Bhattacharjee, Mol Vis 2008; 14:841-850.

Table 3. Haplotype diversity of CYP1B1 coding single nucleotide polymorphisms among primary open-angle glaucoma patients and controls

SI number Haplotype POAG patients (%) Controls (%)
1 C-G-G-T-A 41 10
2 G-T-C-C-A 21.8 29.7
3 C-G-C-C-A 17.5 40
4 C-G-C-C-G 7.5 13.9
5 G-T-G-T-A 6.8 6.4
6 G-T-C-C-G 4.6 0

Haplotypes were constructed using cSNPs in the following order: c.514 C>G, c.727 G>T, c.1666 C>G, c.1719 C>T, and c.1730 A>G. Among major haplotypes, C-G-G-T-A is overrepresented in POAG patients (41%) compared to controls (10%; p=0.0001, by Fisher’s exact test). Hence, C-G-G-T-A represents a potential risk haplotype among POAG patients.

Bhattacharjee, Mol Vis 2008; 14:841-850. http://www.molvis.org/molvis/v14/a100

©2008 Molecular Vision http://www.molvis.org/molvis/

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