Table 7 of
Lopez-Martinez, Mol Vis 2007;
13:862-872.
Table 7. Frequencies of myocilin inferred haplotypes in primary open-angle glaucoma, adult-onset ocular hypertension, and control subjects
Haplotypes were constructed with polymorphisms, -1000, -339(GT)11-19, -306, -224, -126 and -83. Predicted haplotypes with frequencies lower than 2% were not considered. Only haplotypes with frequencies higher than 5% in all groups are shown. The asterisk indicates POAG versus controls and the sharp (hash mark) indicates OHT versus controls.
Haplotype POAG (%) OHT (%) CONTROL (%) p* p# ------------------ -------- ------- ----------- ----- ---- H9 (C-13-G-T-T-G) 19.3 21.1 21.1 0.055 0.83 H7 (C-13-G-C-T-G) 14.2 21.1 20.6 H15 (C-15-A-T-T-G) 11.3 13.2 16.7 H18 (G-15-G-T-T-G) 14.6 9.2 6.1 H4 (C-12-G-T-T-G) 5.2 7.9 5.6 Rest of haplotypes 35.4 27.6 30.0 |