Table 10 of Lopez-Martinez, Mol Vis 2007; 13:862-872.


Table 10. Genotype frequencies of optineurin single nucleotide polymorphisms in primary open-angle glaucoma, adult-onset ocular hypertension, and control subjects

A χ2 test or Fisher's exact test was used to compare genotype frequencies in POAG or OHT patients with control subjects. Genotype frequencies do not statistically differ between cases and controls. The asterisk indicates POAG versus controls and the sharp (hash mark) indicates OHT versus controls.

                      Allele1/   POAG (%)   OHT (%)   CONTROL (%)
        SNP           Allele2    (n=110)    (n=40)      (n=98)       p*     p#
-------------------   --------   --------   -------   -----------   ----   ----
c.412G>A (Thr34Thr)     G/G        44.3       56.6       49.9       0.06   0.20
                        G/A        44.3       36.6       31.0
                        A/A        11.4        6.6       19.0
c.433G>A (Leu41Leu)     G/G        98.2      100.0       94.6       0.25   0.32
                        G/A         1.8        0.0        5.3
                        A/A         0.0        0.0        0.0

Lopez-Martinez, Mol Vis 2007; 13:862-872 <http://www.molvis.org/molvis/v13/a94/>
©2007 Molecular Vision <http://www.molvis.org/molvis/>
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