Figure 7. Avascular retinal area and clock hours of intravitreous neovascularization and capillary densities of apocynin treated pups

A: Percent avascular retinal area in oxygen-induced retinopathy (OIR) after intraperitoneal (IP) injections with apocynin once every 24 h from p12 to p17 and assayed at p18 was significantly reduced compared to phosphate buffered saline (PBS) injected pups (* p=0.017, Student's t-test; n=11 retinas each). B: Clock hours of intravitreous neovascularization (IVNV) in OIR retinas after IP injections with apocynin once every 24 h from p12 to p17 and assayed at p18 were not significantly different to PBS injected pups (p=0.26; Mann-Whitney test, n=11). C: At p18, capillary densities did not differ between apocynin and PBS injected treatment groups. (p=0.37; Student t-test, n=6).