Figure 1. Haplotypes of markers flanking GLC1M

Based on the published pedigree structure [24], only seven family members who are informative for refinement of the critical region of GLC1M were included in this figure. Squares denote male family members while circles indicate females. Shaded shapes are family members with juvenile open angle glaucoma. Markers S33N, rs889022, and G659G are single nucleotide polymorphisms of NRG2.A rectangle encases segregating haplotypes. The haplotype for subject III:9 was inferred by using known genotypes from her offspring and husband.