Figure 7. Albumin nanoparticles allow efficient in vitro gene transfection and expression

A: In vitro transfection efficiency with pSOD-encapsulated human serum albumin nanoparticles (HSA NP) in ARPE-19 cells. Following 6 h incubation with the gene delivery system, transfection was assessed at 48 h post transfection using flow cytometry (10,000 cell count per event). Data are expressed as mean±SD for n=3. ** Indicates significant difference from the control group at p less than or equal to 0.01. B: Enhanced SOD1 activity after cell transfection with 5 μg of pSOD encapsulated in HSA NP. Following 6 h incubation with the gene delivery system, SOD activity was assessed 48 h post transfection using a SOD activity assay kit. Data are expressed as mean±SD for n=3. ** Indicates significant difference from the control group at p less than or equal to 0.01.