Table 1 of
Wang, Mol Vis 2007;
13:719-723.Table 1 of
Wang, Mol Vis 2007;
13:719-723.
Table 1. Genotype and allele frequencies of interleukin-1β (-511) and interleukin-1β (+3953)
There was no statistically significant difference in genotype frequency (GF) or allele frequency (AF) distribution of the two polymorphisms between NTG and control subjects. The breakdown was as follows: For IL-1β -511, the AF was p=0.3 and the GF was p=0.4; for IL-1? +3953, the AF was p=0.88 and the GF was p=0.98.
Genotype NTG (%) n= 231 Control (%) n=245 χ2 p-value
------------------ -------------- ----------------- ---- -------
IL-1β (-511)
Genotype
C/C 70 (30.3%) 61 (24.9%)
C/T 108 (46.8%) 125 (51.0%) 1.77 0.4
T/T 53 (22.9%) 59 (24.1%)
Allele
C 248 (53.7%) 247 (50.4%) 1.02 0.3
T 214 (46.3%) 243 (49.6%)
IL-1β (+3953)
Genotype
C/C 214 (93.8%) 226 (92.2%)
C/T 16 ( 6.9%) 18 ( 7.3%) 0.03 0.98
T/T 1 ( 0.4%) 1 ( 0.4%)
Allele
C 444 (96.1%) 470 (95.9%) 0.02 0.88
T 18 ( 3.9%) 20 ( 4.1%)
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