Table 5. Reported frequencies of known polymorphisms and population variants in the CYP1B1, MYOC, OPTN, and OPTC genes in primary open-angle glaucoma patients and controls from different populations

We did not look for another MYOC promoter polymorphism at nt -1000 (-1000C>G; MYOC.mt1; asterisk) in our primary open-angle glaucoma (POAG) data set because Alward et al. [43] and Özgül et al. [44] have observed that it is not a risk factor for the development of glaucoma in patients from the U.S.A. or Turkey, respectively.