Figure 6 of
Fradot, Mol Vis 2007;
13:594-601.Figure 6 of
Fradot, Mol Vis 2007;
13:594-601.
Figure 6. Molecular model of NR2E3LBD
Homology modeling of the NR2E3LBD based on the RARLBD crystal structure. Highlighted are several residues that mutated in enhanced S-cone syndrome. The residue R385, shown in green, was predicted to localize in the ligand hydrophobic pocket. Mutation of W234, shown in red, was predicted to modify the ligand pocket conformation.
