Table 1 of
Rutland, Mol Vis 2007;
13:47-56.
Table 1. Proportions and tissue volumes of tissue types in wild-type and VEGF-A188 transgenic mice
Proportion of total ocular tissue types in wild-type (n=5) and VEGF-A188 transgenic (n=6) mice. Values represent mean±SEM. Statistical comparisons between groups were performed using one-way ANOVA, with significant differences designated by an asterisk. Significance was accepted as p<0.05.
Proportion of Proportion of Volume of Volume of tissue tissue tissue tissue (wild-type; (transgenic; Increase/ (wild-type; (transgenic; Increase/ Tissue n=5) n=6) decrease p value n=5) n=6) decrease p-value ----------------- --- ------------- ------------- --------- ------- ------------- ------------- --------- ------- Retina A 0.3635±0.0185 0.4903±0.0529 1.35 fold 0.03* 0.4386±0.0236 0.3572±0.0203 19% 0.04* increase decrease Cornea B 0.0370±0.0064 0.0454±0.0040 - 0.2 0.0430±0.0064 0.0346±0.0047 - 0.3 Optic Stalk C 0.0066±0.0010 0.0109±0.0013 1.65 fold 0.01* 0.0077±0.0012 0.0080±0.0011 - 0.8 increase Aqueous D 0.0026±0.0012 0.0085±0.0044 - 0.1 0.4243±0.0292 0.2215±0.0582 48% 0.01* decrease Vitreous E 0.3599±0.0240 0.2611±0.0336 - 0.1 0.0031±0.0013 0.0087±0.0046 0.3 Hyaloid blood F 0.0037±0.0005 0.0148±0.0019 4 fold 0.0001* 0.0043±0.0005 0.0110±0.0013 2.56 fold 0.001* vessels (TVL) increase increase Anteria hyaloidea G 0.0052±0.0015 0.0115±0.0020 2.2 fold 0.003* 0.0061±0.0016 0.0084±0.0013 - 0.3 propria (AHP) increase Iris H 0.0193±0.0071 0.0336±0.0152 1.7 fold 0.02* 0.0229±0.0047 0.0252±0.0031 - 0.6 increase Lens stroma I 0.2023±0.0037 0.0779±0.0041 62% 0.004* 0.2387±0.0113 0.0691±0.0212 71% 0.001* decrease Decrease Lens hemorrhage J 0±0 0.0460±0.0085 Not 0.0001* 0±0 0.0406±0.0126 Not 0.01* observed observed in in wild-type wild-type Total Lens I+J 0.2023±0.0071 0.1239±0.0029 39% 0.01* 0.2387±0.0113 0.1098±0.0337 54% 0.008* decrease decrease Total Blood F+G 0.0089±0.0017 0.0263±0.0027 2.96 fold 0.0001* 0.0104±0.0019 0.0194±0.0019 1.87 fold 0.009* Vessels dncrease increase |