Table 1 of Rutland, Mol Vis 2007; 13:47-56.


Table 1. Proportions and tissue volumes of tissue types in wild-type and VEGF-A188 transgenic mice

Proportion of total ocular tissue types in wild-type (n=5) and VEGF-A188 transgenic (n=6) mice. Values represent mean±SEM. Statistical comparisons between groups were performed using one-way ANOVA, with significant differences designated by an asterisk. Significance was accepted as p<0.05.

                          Proportion of   Proportion of                         Volume of       Volume of
                             tissue          tissue                                tissue          tissue
                           (wild-type;    (transgenic;    Increase/              (wild-type;     (transgenic;    Increase/
     Tissue                   n=5)            n=6)        decrease    p value       n=5)            n=6)        decrease    p-value
-----------------   ---   -------------   -------------   ---------   -------   -------------   -------------   ---------   -------
Retina               A    0.3635±0.0185   0.4903±0.0529   1.35 fold   0.03*     0.4386±0.0236   0.3572±0.0203      19%      0.04*
                                                          increase                                              decrease
Cornea               B    0.0370±0.0064   0.0454±0.0040       -       0.2       0.0430±0.0064   0.0346±0.0047       -       0.3
Optic Stalk          C    0.0066±0.0010   0.0109±0.0013   1.65 fold   0.01*     0.0077±0.0012   0.0080±0.0011       -       0.8
                                                          increase
Aqueous              D    0.0026±0.0012   0.0085±0.0044       -       0.1       0.4243±0.0292   0.2215±0.0582      48%      0.01*
                                                                                                                decrease
Vitreous             E    0.3599±0.0240   0.2611±0.0336       -       0.1       0.0031±0.0013   0.0087±0.0046               0.3
Hyaloid blood        F    0.0037±0.0005   0.0148±0.0019   4 fold      0.0001*   0.0043±0.0005   0.0110±0.0013   2.56 fold   0.001*
vessels (TVL)                                             increase                                              increase
Anteria hyaloidea    G    0.0052±0.0015   0.0115±0.0020   2.2 fold    0.003*    0.0061±0.0016   0.0084±0.0013       -       0.3
propria (AHP)                                             increase
Iris                 H    0.0193±0.0071   0.0336±0.0152   1.7 fold    0.02*     0.0229±0.0047   0.0252±0.0031       -       0.6
                                                          increase
Lens stroma          I    0.2023±0.0037   0.0779±0.0041      62%      0.004*    0.2387±0.0113   0.0691±0.0212      71%      0.001*
                                                          decrease                                              Decrease
Lens hemorrhage      J    0±0             0.0460±0.0085      Not      0.0001*   0±0             0.0406±0.0126      Not      0.01*
                                                          observed                                              observed
                                                              in                                                   in
                                                          wild-type                                             wild-type

Total Lens          I+J   0.2023±0.0071   0.1239±0.0029      39%      0.01*     0.2387±0.0113   0.1098±0.0337      54%      0.008*
                                                          decrease                                              decrease
Total Blood         F+G   0.0089±0.0017   0.0263±0.0027   2.96 fold   0.0001*   0.0104±0.0019   0.0194±0.0019   1.87 fold   0.009*
Vessels                                                   dncrease                                              increase

Rutland, Mol Vis 2007; 13:47-56 <http://www.molvis.org/molvis/v13/a6/>
©2007 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535