Figure 6 of Rosenthal, Mol Vis 2007; 13:443-456.

Figure 6. Vascular endothelial growth factor secretion

A: Increase of vascular endothelial growth factor (VEGF) concentration in the test solution over time (each group: n=3 which represent 3 cultures from 3 different patients). B: Effect of L-type Ca2+ channel modulation (inhibition: nifedipine, (+)BayK8644 enantiomer; activation: (-)BayK8644 enantiomer) on VEGF secretion by cells from eyes without CNV (8 h values). C: Effect of L-type channel modulation (inhibition: nifedipine, 10-5 (+)BayK8644 enantiomer; activation: 10-5 (-)BayK 8644 enantiomer) on VEGF secretion rate in cells from choroidal neovascularization (CNV) membranes (8 h values). D: Effect of nifedipine on basic fibroblast growth factor (bFGF) induced rise in the VEGF secretion rate by cells from eyes without CNV (left bars) and from CNV membranes (right bars; 8 h values).

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