Figure 4 of
Liu, Mol Vis 2007;
13:31-38.
Figure 4. Effects of stable expression of the β5 proteasome subunit on the viability of LECs after H2O2 treatment
Cell viability was measured by the MTT method 4 h after addition of H2O2. Treatment of LECs with H2O2 resulted in a dose-dependent decrease in viability in both β5 expressing cells and nonexpressing controls. Stable expression of β5 resulted in a significant protective effect against H2O2 toxicity in LECs. Similar results were obtained in the three independent cell lines analyzed.