Figure 11. Measurements of percentage retinal detachment and outer nuclear layer dysplasia in electron micrographs from 5 week-old p27^+/+ and p27^-/- mice

In each of the wild-type retinas examined, there is virtually no evidence of either detachment or dysplasia (n=4). Mutant retinas, on the other hand, exhibit both types of structural abnormality in varying amounts. However, loss of RPE-photoreceptor interdigitation appears to be uncorrelated with the magnitude of outer nuclear layer dysplasia (r=-0.189).