Table 1. Levels of A2E and its precursors in eyecups of 9-month-old wt/wt and Stgd3/wt mice

Chloroform extracts from eyecups of individual mice were analyzed for retinal fluorophores using high performance liquid chromatography as described previously in reference [23]. Levels of A2E and its precursors (A2E-H2 and A2PE) are expressed as means in pmoles per eyecup±standard deviation. Six mice were analyzed per group.