Table 1 of Hudson, Mol Vis 2007; 13:2339-2343.


Table 1. Comparison of X-inactivation ratios in affected and unaffected women carrying Leber hereditary optic neuropathy mtDNA mutations and 96 control subjects

Frequency of different degrees of X-skewing in affected and unaffected women harbouring Leber hereditary optic neuropathy mtDNA mutations and healthy controls. There was no significant difference between the different groups.

                                                                 Comparison of LHON
                                                                 mutation carriers
                       LHON mtDNA mutation                          with controls
                       ---------------------          Control    ------------------
X-inactivation ratio   Affected   Unaffected   p a    subjects   p b    p c    p d
--------------------   --------   ----------   ----   --------   ----   ----   ----
<30:70 or >70:30          14         38        0.41     28       0.67   0.76   0.29
<20:80 or >80:20          9          27        0.82     12       0.19   0.20   0.13
<10:90 or >0:90           4          13        1.0       6       0.48   0.47   0.49
<5:95 or >9:95            0           3        1.0       3       0.55   0.68   0.42
Total                     34        116                 79

Hudson, Mol Vis 2007; 13:2339-2343 <http://www.molvis.org/molvis/v13/a265/>
©2007 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535