Table 1 of
Hudson, Mol Vis 2007;
13:2339-2343.
Table 1. Comparison of X-inactivation ratios in affected and unaffected women carrying Leber hereditary optic neuropathy mtDNA mutations and 96 control subjects
Frequency of different degrees of X-skewing in affected and unaffected women harbouring Leber hereditary optic neuropathy mtDNA mutations and healthy controls. There was no significant difference between the different groups.
Comparison of LHON mutation carriers LHON mtDNA mutation with controls --------------------- Control ------------------ X-inactivation ratio Affected Unaffected p a subjects p b p c p d -------------------- -------- ---------- ---- -------- ---- ---- ---- <30:70 or >70:30 14 38 0.41 28 0.67 0.76 0.29 <20:80 or >80:20 9 27 0.82 12 0.19 0.20 0.13 <10:90 or >0:90 4 13 1.0 6 0.48 0.47 0.49 <5:95 or >9:95 0 3 1.0 3 0.55 0.68 0.42 Total 34 116 79 |