Table 1 of
Mojumder, Mol Vis 2007;
13:2163-2182.Table 1 of
Mojumder, Mol Vis 2007;
13:2163-2182.
Table 1. Conservation of peptide immunogens used to generate antibodies against Nav1.1, Nav1.2, and Nav1.6 across rat Nav1 α-subunit family proteins
Table showing the protein names, gene names and accession numbers for members of the rat Nav1 (α-subunit) family of sodium channels. To determine the percent amino acid identity, the amino acid sequences of the three peptide immunogens used to generate the antibodies against Nav1.1, Nav1.2, and Nav1.6 were aligned pairwise with the full length sequence of each of the Nav1 proteins using AlignX.
Amino acid identity
Gene Accession ------------------------
Protein name number Nav1.1 Nav1.2 Nav1.6
------- ------ --------- ------ ------ ------
Nav1.1 Scn1a NP_110502 100.0 59.2 38.9
Nav1.2 Scn2a NP_036779 50.6 100.0 50.0
Nav1.3 Scn3a NP_037251 48.1 73.4 33.3
Nav1.4 Scn4a NP_037310 21.0 40.0 22.2
Nav1.5 Scn5a NP_037257 25.3 42.0 33.3
Nav1.6 Scn8a NP_062139 18.5 44.4 100.0
Nav1.7 Scn9a NP_579823 38.3 68.5 27.8
Nav1.8 Scn10a NP_058943 16.5 32.3 27.8
Nav1.9b Scn11a NP_062138 13.6 12.9 27.8
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