Table 3 of
Chen, Mol Vis 2007;
13:2142-2147.
Table 3. Diplotype distribution in subjects with diabetes
Diplotypes (i.e., combined individual genotypes for the two polymorphisms 4a/b and G894T). Odds ratio (OR) and 95% confidence interval (CI) were calculated from the 2x2 table of one diplotype or haplotype versus the rest of all the other dipolotypes or haplotypes comparing with diabetes with retinopathy versus diabetes without retinopathy.
Diplotypes
and Diabetes with Diabetes without
haplotypes retinopathy retinopathy OR (95% CI) p-value
------------ ------------- ---------------- --------------- -------
Diplotype(n) 68 300
aG/bG 17 (25.0) 133 (44.3) 0.4 (0.23-0.76) 0.0034
bG/bG 31 (45.6) 94 (31.3) 1.8 (1.07-3.14) 0.0250
aG/aG 9 (13.2) 46 (15.3) 0.8 (0.39-1.82) 0.6613
bG/bT 10 (14.7) 21 (7.0) 2.3 (1.03-5.12) 0.0389
aG/aT 1 (1.5) 2 (0.7) 2.2 (0.20-24.9) 0.5056
aT/bT 0 2 (0.67) - -
bT/bT 0 2 (0.67) - -
Haplotype
bG 89 (65.4) 342 (57.0) 1.4 (0.97-2.11) 0.0712
AG 36 (26.5) 227 (37.8) 0.6 (0.39-0.90) 0.0125
bT 10 (7.4) 27 (4.5) 1.7 (0.80-3.57) 0.1692
aT 1 (0.7) 4 (0.67) 1.1 (0.12-9.95) 0.9300
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