Table 2 of
Chen, Mol Vis 2007;
13:2142-2147.
Table 2. Association study of eNOS gene polymorphisms and diabetic retinopathy
Odds ratio (OR) and 95% confidence interval (CI) were calculated from the 2x2 table of one genotype or allele versus the rest of all the other genotypes or alleles comparing with diabetes with retinopathy versus diabetes without retinopathy.
Genotypes and Diabetes with Diabetes without alleles retinopathy retinopathy OR (95% CI) p-value --------- ------------- ---------------- ---------------- ------- 4a/b Genotypes 68 301 aa 10 (14.7) 48 (16.0) 0.9 (0.43-1.90) 0.7995 ab 17 (25.0) 136 (45.2) 0.4 (0.22-0.73) 0.0023 bb 41 (60.3) 117 (38.9) 2.4 (1.39-4.09) 0.0013 Alleles a 37 (27.2) 232 (38.5) b 99 (72.8) 370 (61.5) 1.7 (1.11-2.50) 0.0131 Glu298Asp Genotypes 68 305 GG 57 (83.8) 263 (86.2) 1.2 (0.59-2.49) 0.6074 GT 11 (16.2) 38 (12.5) 1.4 (0.65-2.81) 0.4119 TT 0 (0) 4 (1.31) 1.0 (1.00-1.02) 0.3424 Alleles G 125 (91.9) 564 (92.5) 1.1 (0.54-2.14) 0.8280 T 11 (8.1) 46 (7.5) |