Table 2 of Chen, Mol Vis 2007; 13:2142-2147.


Table 2. Association study of eNOS gene polymorphisms and diabetic retinopathy

Odds ratio (OR) and 95% confidence interval (CI) were calculated from the 2x2 table of one genotype or allele versus the rest of all the other genotypes or alleles comparing with diabetes with retinopathy versus diabetes without retinopathy.

Genotypes
  and       Diabetes with   Diabetes without
alleles      retinopathy      retinopathy        OR (95% CI)      p-value
---------   -------------   ----------------   ----------------   -------
4a/b
Genotypes     68               301
       aa     10 (14.7)         48 (16.0)       0.9 (0.43-1.90)   0.7995
       ab     17 (25.0)        136 (45.2)       0.4 (0.22-0.73)   0.0023
       bb     41 (60.3)        117 (38.9)       2.4 (1.39-4.09)   0.0013
Alleles a     37 (27.2)        232 (38.5)
        b     99 (72.8)        370 (61.5)       1.7 (1.11-2.50)   0.0131

Glu298Asp
Genotypes     68               305
       GG     57 (83.8)        263 (86.2)       1.2 (0.59-2.49)   0.6074
       GT     11 (16.2)         38 (12.5)       1.4 (0.65-2.81)   0.4119
       TT      0 (0)             4 (1.31)       1.0 (1.00-1.02)   0.3424
Alleles G    125 (91.9)        564 (92.5)       1.1 (0.54-2.14)   0.8280
        T     11 (8.1)          46 (7.5)

Chen, Mol Vis 2007; 13:2142-2147 <http://www.molvis.org/molvis/v13/a243/>
©2007 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535