Table 2 of
Chen, Mol Vis 2007;
13:2142-2147.
Table 2. Association study of eNOS gene polymorphisms and diabetic retinopathy
Odds ratio (OR) and 95% confidence interval (CI) were calculated from the 2x2 table of one genotype or allele versus the rest of all the other genotypes or alleles comparing with diabetes with retinopathy versus diabetes without retinopathy.
Genotypes
and Diabetes with Diabetes without
alleles retinopathy retinopathy OR (95% CI) p-value
--------- ------------- ---------------- ---------------- -------
4a/b
Genotypes 68 301
aa 10 (14.7) 48 (16.0) 0.9 (0.43-1.90) 0.7995
ab 17 (25.0) 136 (45.2) 0.4 (0.22-0.73) 0.0023
bb 41 (60.3) 117 (38.9) 2.4 (1.39-4.09) 0.0013
Alleles a 37 (27.2) 232 (38.5)
b 99 (72.8) 370 (61.5) 1.7 (1.11-2.50) 0.0131
Glu298Asp
Genotypes 68 305
GG 57 (83.8) 263 (86.2) 1.2 (0.59-2.49) 0.6074
GT 11 (16.2) 38 (12.5) 1.4 (0.65-2.81) 0.4119
TT 0 (0) 4 (1.31) 1.0 (1.00-1.02) 0.3424
Alleles G 125 (91.9) 564 (92.5) 1.1 (0.54-2.14) 0.8280
T 11 (8.1) 46 (7.5)
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