Table 3 of
Liu, Mol Vis 2007;
13:2137-2141.Table 3 of
Liu, Mol Vis 2007;
13:2137-2141.
Table 3. Summary and comparison of previous OPA1 studies with current study on primary open-angle glaucoma
POAG: Primary open-angle glaucoma; NTG: normal tension glaucoma; HTG: High tension glaucoma; AAO: age-at-onset; Case/Control indicates the number of cases and controls utilized in each study. Significant association with either rs166850 or rs10451941 SNPs means an association with p-value <0.05 in the referred study.
Significant association
Case/ -----------------------
Study Type control rs166850 rs10451941 Population
---------- ---- ------- -------- ---------- ----------------
[14] NTG 163/186 Yes Yes Caucasian
[15] NTG 61/168 No Yes Caucasian
[16] NTG 65/101 No No Korean
[17] NTG 61/48 No No Barbados
[13] NTG 194/185 No Yes Japanese
[18] HTG 90/186 No No Caucasian
[17] HTG 48/48 No No Barbados
[13] HTG 191/185 No AAO Japanese
This study HTG 279/227 No No Caucasian
This study HTG 193/97 No No African-American
This study HTG 170/138 No No Ghanaian
|