Figure 2. Clusterin in advanced-stage retinal hemangioblastoma associated with von Hippel Lindau

Eye number 8, A-D: Lack of clusterin immunoreactivity is illustrated in the stromal cells (asterisks), but present in glial and vascular components of retinal hemangioblastoma (arrows). A and C were stained with hematoxylin and eosin. B and D were stained with avidin-biotin-peroxidase complex immunostaining. Original magnifications in A and B were x100, in C and D were x200. INL is inner nuclear layer. ONL is outer nuclear layer.