Table 4 of Sun, Mol Vis 2007; 13:2105-2111.


Table 4. Association of APOE allele and retinal microvascular signs in whites

Asterisk beside ε2 indicates carriers of ε2 allele (ε2/ε2, ε2/ε3, and ε2/ε4) while asteriks beside ε4 denotes carriers of ε4 allele (ε3/ε4, ε4/ε4) ε3/ε3 is the referent category. Triple asterisk represents participants with diabetes have been excluded. Double asterisk indicates odds ratio (95% confidence intervals), adjusted for age, gender, fasting glucose (except for retinopathy), current smoking status, body mass index, systolic blood pressure, diastolic blood pressure, total plasma cholesterol, and high density lipoprotein (HDL) cholesterol.

                                             Whites
                           ----------------------------------------
                   APOE     No. of    No. (%)       Multivariable
                  allele   carriers   with sign      OR (95% CI)**
---------------   ------   --------   ----------   ----------------
Retinopathy***    ε2*      226        21 (9.3)     1.18 (0.69-2.02)
                  ε3/ε3    809        64 (7.9)     1.00
                  ε4*      284        22 (7.7)     0.97 (0.56-1.67)
AV nicking        ε2*      291        29 (10.0)    1.70 (1.03-2.83)
                  ε3/ε3    1,036      66 (6.4)     1.00
                  ε4*      350        29 (8.3)     1.74 (1.06-2.84)
Focal narrowing   ε2*      285        27 (9.5)     0.83 (0.52-1.34)
                  ε3/ε3    1,008      106 (10.5)   1.00
                  ε4*      336        27 (8.0)     0.81 (0.51-1.30)

Sun, Mol Vis 2007; 13:2105-2111 <http://www.molvis.org/molvis/v13/a238/>
©2007 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535