Table 2 of Miyazawa, Mol Vis 2007; 13:1912-1919.


Table 2. Frequency of genotypes p.I264V and c.1965-30A>G of WDR36 in patients with high tension glaucoma/normal tension glaucoma and control subjects

Data presented are number of patients, unless otherwise indicated. A/A=homozygous normal; A/G = heterozygous carriers of the WDR36 p.I264V or c.1965-30A>G variant; G/G=homozygous carriers of the WDR36 p.I264V or c.1965-30A>G variant; CI=confidence interval; An asterisk indicates Fisher's exact test. HTG, high tension glaucoma; NTG, normal tension glaucoma.

    WDR36 p.I264V variant         HTG (n=136)        NTG (n=103)      Control (n=118)
-----------------------------   ----------------   ----------------   ---------------
A/A (wild type)                 61/136             74/103             72/118
A/G (heterozygote)              66/136             27/103             41/118
G/G (homozygote)                9/136              2/103              5/118
Odds ratio (95%CI)              1.92 (1.17-3.18)   0.61 (0.35-1.08)
p-value (A/A vs. A/G and G/G)   0.01               0.12

 WDR36 c.1965-30A>G variant       HTG (n=136)        NTG (n=103)      Control (n=118)
-----------------------------   ----------------   ----------------   ---------------
A/A (wild type)                 63/136             76/103             72/118
A/G (heterozygote)              63/136             25/103             41/118
G/G (homozygote)                10/136             2/103              5/118
Odds ratio (95%CI)              1.81 (1.10-2.99)   0.56 (0.31-0.99)
p-value (A/A vs. A/G and G/G)   0.03               0.06

Miyazawa, Mol Vis 2007; 13:1912-1919 <http://www.molvis.org/molvis/v13/a215/>
©2007 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535