Table 2 of
Miyazawa, Mol Vis 2007;
13:1912-1919.
Table 2. Frequency of genotypes p.I264V and c.1965-30A>G of WDR36 in patients with high tension glaucoma/normal tension glaucoma and control subjects
Data presented are number of patients, unless otherwise indicated. A/A=homozygous normal; A/G = heterozygous carriers of the WDR36 p.I264V or c.1965-30A>G variant; G/G=homozygous carriers of the WDR36 p.I264V or c.1965-30A>G variant; CI=confidence interval; An asterisk indicates Fisher's exact test. HTG, high tension glaucoma; NTG, normal tension glaucoma.
WDR36 p.I264V variant HTG (n=136) NTG (n=103) Control (n=118) ----------------------------- ---------------- ---------------- --------------- A/A (wild type) 61/136 74/103 72/118 A/G (heterozygote) 66/136 27/103 41/118 G/G (homozygote) 9/136 2/103 5/118 Odds ratio (95%CI) 1.92 (1.17-3.18) 0.61 (0.35-1.08) p-value (A/A vs. A/G and G/G) 0.01 0.12 WDR36 c.1965-30A>G variant HTG (n=136) NTG (n=103) Control (n=118) ----------------------------- ---------------- ---------------- --------------- A/A (wild type) 63/136 76/103 72/118 A/G (heterozygote) 63/136 25/103 41/118 G/G (homozygote) 10/136 2/103 5/118 Odds ratio (95%CI) 1.81 (1.10-2.99) 0.56 (0.31-0.99) p-value (A/A vs. A/G and G/G) 0.03 0.06 |