Table 2 of Kamphuis, Mol Vis 2007; 13:1892-1901.


Table 2. Gene ontology results for genes displaying a differential change as a result of ischemic preconditioning

Full gene names and fold-change details are given in Appendix 2. In the table headings, C is a list of the number of signatures genes assigned to gene ontology terms, P presents Fisher exact p-value for each biological process, and E.S. represents enrichment score for the cluster.

   Biological process       Group   C        P       ES                                   Genes
-------------------------   -----   --   --------   ----   ----------------------------------------------------------------------
tRNA aminoacylation         1 h     8    0.003      2.51   Cars, Farslb, Iars, Kars, Lars, Nars, Rarsl, Tars
Amino acid metabolism       1 h     17   0.042      1.17   Cars, Farslb, Iars, Kars, Lars, Nars, Rarsl, Tars, Bcat1, RGD1306332,
                                                           Slc7a1, Hibadh, Itgb2, Ppat, Tyrp1, Psat1, Ddah1
tRNA aminoacylation         2 h     7    0.002      2.75   Cars, Farslb, Iars, Lars, Nars, Rarsl, Sars2, Tars
tRNA aminoacylation
(tRNA metabolism)           6 h     5    0.005      2.44   Farslb, Iars, Nars, Rarsl, Tars, Wdr46, (Rg9mtd1, Trnt1)
tRNA aminoacylation         12 h    6    6.4 10-4   2.42   Cars, Iars, Lars, Nars, Rarsl, Tars, Wdr46
Immune cell chemotaxis      1 h     5    0.009      1.89   Cxcl2, Il1b, Itgam, Itgb2, Spp1
Complement activation,      2 h     4    0.036      0.98   C1qb, C1s, C4a, Serping1
classical pathway
Immune response             6 h     16   0.029      1.74   Anxa1, C1qb, C3, Cd48, Cd53, Cxcl10, Fcgr2b, Gpsm3, Il6, Lyz, Maf,
                                                           Sele, Serping1, Stat3, Tnfrsf1a, Vezf1
Immune response             12 h    35   3.3 10-8   7.41   Anxa1, Arts1, Atp6ap2, C1qb, C3, C5r1, Ccl17, Ccnd3, Cd3g, Cd53, Cd97,
                                                           Coro1a, Crh, Cxcl10, Egr1, Fcgr1, Fcgr2b, Fcgr3, Fn1, Ikbke, Il1b,
                                                           Itgam, Itgb2, Lsp1, Lyz, Oas1, Penk-rs, Ptprc, S100a8, Spp1, Stat3,
                                                           Tlr2, Tnfrsf1a, Tnfrsf6, Wwp1
Apoptosis/programmed cell   2 h     32   0.036      1.24   Aldh1a3, Anxa1, Api5, Bcl2a1, Bdnf, Birc1b, Cdkn1a, Cfl1, Cul5, Dedd,
death                                                      Emp1, Fgfr1, Hip1, Igf1, Itgb2, Lcn2, LOC500292, Mal, Nr4a1, Perp,
                                                           Phlda1, Ppp1r13b, RGD1309729, Rhob, Ripk3, Sgpp1, Son, Spp1, Tesk2,
                                                           Tnfrsf1a
Anti-apoptosis              2 h     11   0.042      1.36   Anxa1, Api5, Bcl2a1, Bdnf, Birc1b, Cdkn1a, Cfl1, Fgfr1, Igf1, Son,
                                                           Spp1
Apoptosis/programmed cell   6 h     12   0.035      1.13   Aldh1a3, Anxa1, Bok, Hrpap20, Igf1, Il6, Lyz, Madd, Perp, Sgpp1,
death                                                      Tnfrsf1a, Tradd
Apoptosis/programmed cell   12 h    22   0.002      2.53   Aldh1a3, Anxa1, Api5, Bcl2a1, Crh, Cd3g, Cul2, Cul3, Dedd, Fcgr1,
death                                                      Fcgr3, Il1b, Itgb2, Lsp1, Mal, Nr4a1, Ptpn6, RGD1309729, Sphk1, Spp1,
                                                           Tnfrsf1a, Tnfrsf6
Anti-apoptosis              12 h    5    0.043      1.06   Anxa1, Api5, Bcl2a1, Sphk1, Spp1

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