Table 2 of
Kamphuis, Mol Vis 2007;
13:1892-1901.
Table 2. Gene ontology results for genes displaying a differential change as a result of ischemic preconditioning
Full gene names and fold-change details are given in Appendix 2. In the table headings, C is a list of the number of signatures genes assigned to gene ontology terms, P presents Fisher exact p-value for each biological process, and E.S. represents enrichment score for the cluster.
Biological process Group C P ES Genes ------------------------- ----- -- -------- ---- ---------------------------------------------------------------------- tRNA aminoacylation 1 h 8 0.003 2.51 Cars, Farslb, Iars, Kars, Lars, Nars, Rarsl, Tars Amino acid metabolism 1 h 17 0.042 1.17 Cars, Farslb, Iars, Kars, Lars, Nars, Rarsl, Tars, Bcat1, RGD1306332, Slc7a1, Hibadh, Itgb2, Ppat, Tyrp1, Psat1, Ddah1 tRNA aminoacylation 2 h 7 0.002 2.75 Cars, Farslb, Iars, Lars, Nars, Rarsl, Sars2, Tars tRNA aminoacylation (tRNA metabolism) 6 h 5 0.005 2.44 Farslb, Iars, Nars, Rarsl, Tars, Wdr46, (Rg9mtd1, Trnt1) tRNA aminoacylation 12 h 6 6.4 10-4 2.42 Cars, Iars, Lars, Nars, Rarsl, Tars, Wdr46 Immune cell chemotaxis 1 h 5 0.009 1.89 Cxcl2, Il1b, Itgam, Itgb2, Spp1 Complement activation, 2 h 4 0.036 0.98 C1qb, C1s, C4a, Serping1 classical pathway Immune response 6 h 16 0.029 1.74 Anxa1, C1qb, C3, Cd48, Cd53, Cxcl10, Fcgr2b, Gpsm3, Il6, Lyz, Maf, Sele, Serping1, Stat3, Tnfrsf1a, Vezf1 Immune response 12 h 35 3.3 10-8 7.41 Anxa1, Arts1, Atp6ap2, C1qb, C3, C5r1, Ccl17, Ccnd3, Cd3g, Cd53, Cd97, Coro1a, Crh, Cxcl10, Egr1, Fcgr1, Fcgr2b, Fcgr3, Fn1, Ikbke, Il1b, Itgam, Itgb2, Lsp1, Lyz, Oas1, Penk-rs, Ptprc, S100a8, Spp1, Stat3, Tlr2, Tnfrsf1a, Tnfrsf6, Wwp1 Apoptosis/programmed cell 2 h 32 0.036 1.24 Aldh1a3, Anxa1, Api5, Bcl2a1, Bdnf, Birc1b, Cdkn1a, Cfl1, Cul5, Dedd, death Emp1, Fgfr1, Hip1, Igf1, Itgb2, Lcn2, LOC500292, Mal, Nr4a1, Perp, Phlda1, Ppp1r13b, RGD1309729, Rhob, Ripk3, Sgpp1, Son, Spp1, Tesk2, Tnfrsf1a Anti-apoptosis 2 h 11 0.042 1.36 Anxa1, Api5, Bcl2a1, Bdnf, Birc1b, Cdkn1a, Cfl1, Fgfr1, Igf1, Son, Spp1 Apoptosis/programmed cell 6 h 12 0.035 1.13 Aldh1a3, Anxa1, Bok, Hrpap20, Igf1, Il6, Lyz, Madd, Perp, Sgpp1, death Tnfrsf1a, Tradd Apoptosis/programmed cell 12 h 22 0.002 2.53 Aldh1a3, Anxa1, Api5, Bcl2a1, Crh, Cd3g, Cul2, Cul3, Dedd, Fcgr1, death Fcgr3, Il1b, Itgb2, Lsp1, Mal, Nr4a1, Ptpn6, RGD1309729, Sphk1, Spp1, Tnfrsf1a, Tnfrsf6 Anti-apoptosis 12 h 5 0.043 1.06 Anxa1, Api5, Bcl2a1, Sphk1, Spp1 |