Figure 4 of Redmond, Mol Vis 2007; 13:1813-1821.

Figure 4. Effect of variation at aa446 on predicted tertiary structure of RPE65, modeled on apocarotenoid oxygenase, and on secondary structure prediction of RPE65

A: R446/L450 (dog wildtype). B: R446/M450. C: K446/L450 (mouse wildtype). D: K446/M450. Note the interactions of R446 and M450 with the predicted hydrogen-bonded Q414 and E456 pair. RPE65 residues are plotted onto the ACO backbone [26] using DeepView.

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