Figure 2 of
Redmond, Mol Vis 2007;
13:1813-1821.Figure 2 of
Redmond, Mol Vis 2007;
13:1813-1821.
Figure 2. Effect of methionine at aa450 on activity and expression of RPE65
A: 11-cis retinol production in 293-F cells transfected with constructs expressing wildtype and L450M mutants of dog and mouse RPE65. L450M mutant activities are expressed as percentage of wildtype RPE65 activity (n=4). B: Immunoblot analysis of 293-F cells expressing wildtype and L450M mutants of dog and mouse RPE65 (top panel) and of CRALBP (bottom panel). WT represents wildtype; d represents dog; m represents mouse.
