Figure 1 of
Li, Mol Vis 2007;
13:1758-1768.
Figure 1. Schematic diagram of αA-crystallin mutant sequences
For the six truncation mutants, the NH2-terminal sequence (residues 1-50) was replaced with a short hydrophilic leader sequence to improve stability [49], and the IPV triad in the COOH-terminal extension was altered as shown. An additional set of mutants retained the native NH2-terminal sequence, but the IPV triad was altered.