Table 3 of
Popp, Mol Vis 2007;
13:164-173.Table 3 of
Popp, Mol Vis 2007;
13:164-173.
Table 3. Genes whose expression was significantly (p less than or equal to 0.05) altered by more than two-fold
Mean log2 difference is the level of gene expression in tissue surrounding the surgical site compared to similar tissue from the nonsurgically treated control eye. The p-value represents the level of significance in treatment means, hit definition the name of the most homologous gene and E-value the level of confidence that the matched name is incorrect. Also listed are the GeneOntology Consortium terms for biological process associated with the most homologous gene.
Mean log2
Probe name p-value difference Hit definition E-value GO biological process term
------------- ------- ---------- ---------------------------- ---------- --------------------------
UF_Oc_n_41285 0.001 4.48 Serum amyloid A-3 protein 0 Acute-phase response
UF_Oc_n_41565 0.007 3.11 Interleukin-1 beta 0 Antimicrobial humoral
(IL-1 beta) response, inflammatory
response
UF_Oc_n_41308 0.020 2.81 Alpha-1-acid glycoprotein 0 Acute-phase response,
(Orosomucoid) inflammatory response
UF_Oc_c_40013 0.000 2.07 Cathepsin K (EC 3.4.22.-) 0 Lysosome, proteolysis
and peptidolysis
UF_Oc_r_30389 0.012 1.87 Similar to Ldb1a 8.46E-37
UF_Oc_n_41283 0.008 1.85 92 kDa type IV collagenase 0 Collagen catabolism,
(Matrix metalloproteinase-9) collagenase activity
UF_Oc_c_40416 0.002 1.83 Neutrophil granules matrix 1.40E-20 Defense response, innate
glycoprotein SGP28 immune response,
cell-cell adhesion
UF_Oc_r_30382 0.003 1.74 Ceruloplasmin At 3.0 1.04E-38 oxidoreductase activity
angstrom
UF_Oc_c_40419 0.042 1.37 Lumican 5.93E-20 Collagen binding,
collagen fibril
organization
UF_Oc_c_40194 0.010 1.32 Lysozyme C (1,4-beta- 0 Lysozyme activity,
N-acetylmuramidase C) response to bacteria,
cell wall catabolism
UF_Oc_n_31501 0.011 1.28 Fibronectin 0 Acute-phase response,
inflammatory response,
cell adhesion and
migration, extracellular
matrix structural
constituent
UF_Oc_n_41531 0.016 1.20 Serum amyloid A-1 0 Acute-phase response
UF_Oc_c_40715 0.038 1.17 major facilitator family 1.18908
transporter
UF_Oc_r_30531 0.003 1.11 Cathepsin B 3.13E-06 Negative regulation of
inflammatory response,
proteolysis and
peptidolysis
UF_Oc_n_41428 0.020 1.05 Cathepsin E (EC 3.4.23.34) 0 Positive regulation of
cytokine secretion,
proteolysis and
peptidolysis
UF_Oc_c_40213 0.048 1.05 Lumican 0 Collagen binding,
collagen fibril
organization
UF_Oc_n_41539 0.009 1.04 Cystatin B 0
UF_Oc_c_40622 0.010 -1.00 NADH dehydrogenase subunit 4 0.335226
UF_Oc_n_41502 0.022 -1.05 Voltage-dependent anion 0 Mitochondrial outer
channel 1 membrane
UF_Oc_n_41237 0.006 -1.06 Mono (ADP-ribosyl) 0
transferase
UF_Oc_c_40346 0.040 -1.25 Corneal endothelium specific 6.09E-38
protein 1
UF_Oc_n_41352 0.020 -1.35 Cytochrome P450 2A10 0 Electron transport,
(CYPIIA10) oxidoreductase activity
on paired donors, oxygen
binding
UF_Oc_r_30067 0.004 -1.52 Alpha-actinin-2-associated 0
LIM protein
UF_Oc_c_40478 0.024 -1.66 Corneal endothelium specific 6.32E-09
protein 1
UF_Oc_r_30565 0.006 -1.70 Hypothetical protein 0.00204271
UF_Oc_n_41489 0.008 -2.06 Chondromodulin-I (Leukocyte 0 Cell differentiation,
cell-derived chemotaxin 1) extracellular space
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