Figure 2. Detection of D380A and P370L MYOC mutations by direct polymerase chain reaction DNA sequencing

A: Representative electropherogram of the heterozygous A>C transversion found in Spanish subjects with JOAG. B: Electropherograms of the heterozygous C>T transition detected in the father and daughter from the Colombian JOAG family GJH6. Control electropherograms are shown below for comparison purposes. The arrows indicate the position of the mutations.