Figure 2 of Yen, Mol Vis 2007; 13:1627-1634.

Figure 2. Splice sites of MYOC transcripts were predicted by a neural network prediction system

A: The mutation of c.604+228A>T in MYOC leads the neural network value of a novel accept splice site at c.604+233-234AG of MYOC (star) to increase from 0 to 0.71. B: c.604+228A>T mutant of MYOC predicted that a cDNA with a 234 nucleotide fragment between 604 and 605 would be produced. The black bar indicates sequence of insert cDNA sequence. C: Predicted protein sequences coded from MYOC of normal or the c.604+228A>T mutation.

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