Table 7 of
Ayala-Lugo, Mol Vis 2007;
**13**:151-163.

Table 7. Aggregate statistical summaries in Asian populations screened for R545Q

Results from computing the upper and lower 95% confidence interval bounds around the odds ratio indicate that none of the Asian divisions are statistically different from an odds ratio of 1. The Woolf test for homogeneity indicates that across studies within each ancestry group the odds ratios are statistically equivalent (i.e., homogeneous, because a p value less than 0.05 would indicate heterogeneity [25]). A two-sided Fisher's exact test on the pooled frequencies was computed for those instances when the Woolf test indicated homogeneity at the 0.05 level. The ancestry groups are collated for China from Chen et al. [14] and Fan et al. [15]; and for Japan from Alward et al. [11], Funayama et al. [16], Fuse et al. [17], Tang et al. [20], and Umeda et al. [21]. The Asia listing includes data pooled from the China and Japan categories. Only Fan et al. [15] report on NTG for China.

Fisher's Cases Controls Percent 95% CI bounds Woolf exact ------------- ------------- ------------- Odds ------------- test test Ancestry R545Q Total R545Q Total OAG Control ratio Lower Upper p value p value --------- ----- ----- ----- ----- --- ------- ----- ----- ----- ------- -------- China 32 518 24 412 6.2 5.8 0.98 0.57 1.70 0.648 0.89 Japan 62 1208 28 661 5.1 4.2 1.20 0.76 1.90 0.838 0.43 Asia 94 1726 52 1073 5.4 4.8 1.12 0.78 1.58 0.925 0.541 China-NTG 7 106 5 150 6.6 3.3 2.04 0.54 8.41 - 0.244 Japan-NTG 40 705 28 661 5.7 4.2 1.40 0.84 2.33 0.848 0.263 |

Ayala-Lugo, Mol Vis 2007;

©2007 Molecular Vision <http://www.molvis.org/molvis/>

ISSN 1090-0535