Table 5 of
Ayala-Lugo, Mol Vis 2007;
13:151-163.Table 5 of
Ayala-Lugo, Mol Vis 2007;
13:151-163.
Table 5. Frequency of M98K in four populations within our cohort
The total enumeration of both cases and controls is listed in the whole population column. Cases are subdivided according to OAG type, either JOAG, POAG, or NTG. A two-sided Fisher's exact test p value indicated no statistical significance for association between cases and controls in each ancestry category. Woolf's test for homogeneity among the ancestry frequencies yielded a p value of 0.312, indicating that the ancestral subdivisions are statistically similar.
Fisher's
exact
Whole Total test
Ancestry population JOAG POAG NTG OAG Controls p value
--------- ---------- ---- ------ ---- ------ -------- --------
Frequency of mutation in screened samples by population
African 38/169 3/14 14/63 1/4 18/81 20/88 1.0
Asian 32/122 1/2 1/1 1/2 3/5 29/117 0.112
Hispanic 2/62 0/3 1/7 0/1 1/11 1/50 0.331
Caucasian 22/336 3/32 11/159 0/26 14/217 8/116 1.0
Total 94/690 7/51 27/230 2/33 36/314 58/371
Percent of mutation in screened samples by population
African 22.5 21.4 22.2 25.0 22.2 22.7
Asian 26.2 50.0 100.0 50.0 60.0 24.8
Hispanic 3.2 0.0 14.3 0.0 9.1 2.0
Caucasian 6.5 9.4 6.9 0.0 6.5 6.9
Total 3.6 3.7 1.7 6.1 1.5 5.6
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