Table 10 of
Ayala-Lugo, Mol Vis 2007;
13:151-163.Table 10 of
Ayala-Lugo, Mol Vis 2007;
13:151-163.
Table 10. M98K population data sources and screening methods ordered by ancestry
The following methodologies were used to screen samples for variants. We omitted two studies: Wang et al. [40], a Filipino population, and Forsman et al. [34], a population from south Finland, because they are small family-based studies without population data. SSCP: single-strand conformation polymorphism. DHPLC: denaturing high-performance liquid chromatography. HTCSGE: High throughput conformation sensitive gel electrophoresis. RFLP: Restriction Fragment Length Polymorphisms.
Recruitment
locations
Source (population) Methodology Notes
------------ -------------------- ------------------ ------------------------------
China
[14] China-Beijing SSCP->sequencing
[15] China-Hong Kong PCR and
HTCSGE->sequencing
Japan
[11] Japan-Gifu SSCP->sequencing
[16] Japan-Tokyo, PCR-RFLP
Kumamoto, Hamamatsu,
Hiroshima, Niigata
[17] Japan-Miyagi PCR->sequencing
[20] Japan-Yamanashi SSCP->sequencing
[21] Japan-Okayama City sequencing
Asia (other than China and Japan)
[This study] USA-Michigan PCR->sequencing
(Korean, Chinese,
Filipino)
Europe
[This study] USA-Michigan PCR->sequencing Caucasian
[11] Australia-Melbourne, SSCP->sequencing Australian samples
Adelaide, USA-Iowa areCaucasian (D. Mackey,
personal report), Iowa
population >91% Caucasian
according to the State Data
Center of Iowa
[12] England-London PCR-RFLP Caucasian
[13] Australia-New South PCR-RFLP mostly Caucasian
Wales
[32] Sweden-Uppsala and DHPLC, PCR,
Tierps SNaPshot
[18] France-Paris PCR-RFLP French and Moroccan Caucasians
[33] Russia-St. SSCP, PCR
Petersburg
[9] USA-Chicago, PCR->sequencing Unspecified cases with
Connecticut, New and Caucasian controls
Haven,UK-London, SSCP->sequencing
Canada-Toronto
[22] Germany-Tuebingen, PCR-RFLP, DHPLC
Wuerzburg
Hispanic
[This study] USA-Michigan, PCR->sequencing
Florida, Mexico,
Panama, Peru, Chile,
Paraguay
Africa
[This study] USA-Michigan, Ghana- PCR->sequencing African American and African
Accra, Sunyani
India
[19] India-Hyperabad, SSCP->sequencing,
Kolkata DHPLC, PCR--RFLP
[39] India-Chennai PCR->sequencing,
RFLP
Mixed
[38] Australia/Tasmania PCR-RFLP
[36] USA-New England area PCR->sequencing, about 90% Caucasian
DHPLC
[23] USA-Massachusetts, PCR->sequencing about 90% Caucasian
North Carolina
[24] Canada-Toronto PCR-RFLP
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