Table 5 of Bosley, Mol Vis 2007; 13:1516-1528.


Table 5. Mitochondrial DNA and respiratory changes in optic neuritis patients

Shown are nucleotide change(s) from Table 2 for each patient. The "Relative mtDNA Content" column represents the ratio of NADH dehydrogenase subunit 1 to β-actin (see Methods). MRA represents Mitochondrial Respiratory Activity (see Methods). "ND" means not done.

                                 Relative
                                 mtDNA
Patient   Nucleotide change(s)   content     MRA
-------   --------------------   --------   -----
1         None                   2.41       21.93
2         None                   2.22       ND
3         None                   1.80       14.67
4         None                   3.31       22.43
5         None                   1.60       ND
6         None                   1.03       ND
7         14831                  1.94       ND
8         9300                   1.24       ND
9         15924                  4.10       ND
10        9104                   1.08       ND
11        11865                  1.32       16.57
12        4136                   0.96       21.07
13        10946, 13253, 14831    0.85       ND
14        11865                  0.92       17.17
15        4370                   0.95       ND
16        15674                  1.22       15.87
17        9948                   3.51       13.67
18        5089                   3.95       14.30
19        9904                   4.25       ND
20        9948, 14516, 14525     3.92       19.87
21        8813                   3.75       11.77
22        6261, 13936            3.10       16.13
23        6880, 15674            3.10       16.80
24        5516, 15674            2.92       14.40
25        3580                   3.68       ND
26        15968                  2.95       15.03

Bosley, Mol Vis 2007; 13:1516-1528 <http://www.molvis.org/molvis/v13/a168/>
©2007 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535