Figure 7. Expression of integrins in CEC

Mouse CEC were examined for expression of SHPS-1, IAP/CD47, αvβ3, α3, α5, and αv integrins by FACS analysis. Please note that CEC express significant amounts of IAP/CD47 and its ligand SHPS-1. These cells lacked expression of αvβ3 but expressed significant amounts of α3, α5, and αv integrins. The level of α3 was increased in TSP1^-/- CEC while that of α5 and αv was decreased compared to wild type cells. These experiments were performed at least twice with two different isolations of CEC.