Figure 2. Representative retinal sections following immunostaining for albumin

Increased immunostaining was present throughout the retina one week after STZ-induction of diabetes in eyes receiving rAAV-lacZ injection (B) compared to the normal Sprague-Dawley rat (A) where staining was restircted to blood vessels. C: Intravitreal injection of rAAV-angiostatin decreased immunostaining in the retina one week after induction of diabetes. Magnification X200. IPL denotes the inner plexiform layer, INL indicates the inner nuclear layer, and ONL marks the outer nuclear layer.