Table 2 of
Weger, Mol Vis 2007;
13:1274-1279.Table 2 of
Weger, Mol Vis 2007;
13:1274-1279.
Table 2. HTRA serine peptidase 1
This table shows HTRA serine peptidase 1 (HTRA1) -625G>A and complement factor H (CFH) Y402H genotype combination frequencies in patients with exudative age-related macular degeneration (AMD) and control subjects. 95% CI represents 95% confidence interval.
HTRA1 -625 HTRA1 -625 HTRA1 -625
GG GA AA
---------- ---------- ---------- ------------ ------------
Control
subjects CFH 402 YY 51 (32.5%) 22 (14.0%) 5 (3.2%)
YH 38 (24.2%) 24 (15.3%) 3 (1.9%)
HH 10 (6.4%) 4 (2.5%) 0
AMD
patients CFH 402 YY 12 (5.0%) 14 (5.8%) 12 (5.0%)
YH 32 (13.2%) 52 (21.5%) 37 (15.3%)
HH 23 (9.5%) 42 (17.4%) 18 (7.4%)
Odds ratio
(95% CI) CFH 402 YY 1; 2.7 10.2
reference (1.1-6.7) (3.1-33.3)
YH 3.6 9.2 52.4
(1.7-7.8) (4.2-20.2) (14.4-186.4)
HH 9.8 44.6 infinite
(3.7-25.6) (13.8-142.5)
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