Figure 8. Immunohistochemical localization of retinal G protein-coupled receptor splice isoform epitope in the drusen of donor CA-0022

The retinal pigment epithelium-choroid section from a 77-year-old female donor was prepared from frozen tissue and incubated with the DE21 antibody. The purple VIP chromogen indicates positive staining of drusen (solid arrows), Bruch's membrane, and adjacent areas of the choriocapillaris (open arrows). The neural retina was detached (not shown).