Figure 4. Multiple alignment of 11 FOXL2 orthologs

This demonstrated high conservation of residues involved by the p.Tyr81His and p.Ser217Cys mutation. The resource for the 11 FOXL2 orthologs was as follows: human (Homo sapiens, NP_075555), mouse (Mus musculus, NP_036150), pig (Sus scrofa, AAQ91845), rabbit (Oryctolagus cuniculus, AAQ91846), rat (Rattus norvegicus, XP_345976), mole vole (Ellobius lutescens, AAV30684), cow (Bos taurus, NP_001026920), goat (Capra hircus, AAM52099), chicken (Gallus gallus, NP_001012630), zebrafish (Danio rerio, XP_698915), and salmon trout (Oncorhynchus mykiss, AAS87040).